1．教育状况 1979.09-1983.06：吉林农业大学牧医系，畜牧专业，学士 1984.09-1987.06：中国农业大学畜牧系，动物繁殖学专业，硕士 1989.03-1992.06：东北农业大学生物工程系，家畜解剖、组织与胚胎学专业，博士 1998.04-1999.04：加拿大LAVAL大学CRBR研究中心，访问学者 2．工作经历 1987.07-1989.08：东北农业大学动物科技学院，助教 1989.09-1993.08：东北农业大学动物科技学院，讲师 1993.09-1997.08：东北农业大学动物科技学院，副教授 1997.09-至今：东北农业大学动物科技学院，教授，博导，动物繁殖方向和团队带头人。 曾任黑龙江省政协委员、民盟黑龙江省省委委员和民盟东北农业大学主任委员，并历任东北农业大学生命中心主任、学校教学管理中心主任、动物科技学院院长和学校高教所所长等职。 著作论文 一、代表性论文（通讯作者，SCI收录） 1.Chen Wang Peng Zheng, S.O. Adeniran, Mingjun Ma, Fushuo Huang, E.O. Adegoke,Guixue Zhang* Thyroid hormone (T3) is involved in inhibiting the proliferation of newborn calf Sertoli cells via the PI3K/Akt signaling pathway in vitro, Theriogenology 2019,133:1-9, https://doi.org/10.1016/j.theriogenology.2019.04.025 2.E.O Adegoke, S.O Adeniran, Zeng Yue, Wang Xue, Wang Hao, Wang Chen, Zhang Han, Zheng Peng,Zhang Guixue* Pharmacological inhibition of TLR4/NF-kB with TLR4-IN-C34 attenuated microcystin –leucine arginine (MC-LR) toxicity in bovine Sertoli cells, Journal of Applied Toxicology,2019,39(6),832-843 3.Xue Wang E.O.Adegoke Mingjun Ma Fushuo Huang Han Zhang S.O.Adeniran Peng Zheng Guixue Zhang* Influence of Wilms' tumor suppressor gene WT1 on bovine Sertoli cells polarity and tight junctions via non-canonical WNT signaling pathway, Theriogenology,2019,138(15):84-93 4.E.O. Adegoke , Wang Xue, N.S. Machebe, S.O. Adeniran, Wang Hao , Wang Chen, Zhang Han,Zhang Guixue*, Zheng PengSodium Selenite inhibits mitophagy, downregulation and mislocalization of blood-testis barrier proteins of bovine Sertoli cell exposed to microcystin-leucine arginine (MC-LR) via TLR4/NF-kB and mitochondrial signalingpathways blockage, Ecotoxicology and Environmental Safety, 2018 (166): 165 – 175 5.E.O. Adegoke ,Wang Chen, N.S. Machebe , Wang Xue,Wang Hao, S.O.Adeniran ,Zhang Han, Zheng Peng,Zhang Guixue* Microcystin-leucine arginine (MC-LR) induced inflammatory response in bovine sertoli cell via TLR4/NF-kB signaling pathway, Environmental Toxicology and Pharmacology, 2018(63):115-126, 6.E.O Adegoke, Xue Wang,,Hao Wang, Chen wang, Han Zhang,Guixue Zhang*Selenium (Na2SeO3) Upregulates Expression of Immune Genes and Blood–Testis Barrier Constituent Proteins of Bovine Sertoli Cell In Vitro, Biol Trace Elem Res, 2018, 185:332-343 7.Yuhong Gao, Jiuli Zhang, Xiaodan Huang,Guixue Zhang*Glutathione Peroxidase1, Selenoprotein K, and Selenoprotein H May Play Important Roles in Chicken Testes in Response to Selenium Deficiency Biological Trace Element Research. 2017, 179(2):271-276, 8.Ahmed Khalid, Nagam Khudhair, Huang He, Zheng peng, Tian Yaguang Zhang Guixue* Effects of Dietary Selenium Supplementation on Seminiferous Tubules and SelW, GPx4, LHCGR, and ACE Expression in Chicken Testis, Biological Trace Element Research. 2016,173(1):202–209 9.Ahmed Khalid, Yu Na, Zhang Jinyou, Nagam Khudhair, Zheng peng, Zhao xunwu,Zhang Guixue*Responses of Chicken Sertoli Cells and Fibroblasts after Transfection with Plasmids pEGFP-N3-HNP-1 Pakistan Veterinary Jounal 2015,35(4):504-509 10.Jin-You Zhang, Yi Wu, Shuan Zhao, Zhen-Xing Liu, Shen-Ming Zeng,Gui-Xue Zhang* Lysosomes are involved in induction of steroidogenic acute regulatory protein (StAR) gene expression and progesterone synthesis through low density lipoprotein in cultured bovine granulosa cells, Theriogenology,2015, 84:811-817 二、著作（主编） 1．《Reproductive Science and Technology in Animals》双语教材，黑龙江教育出版，2014.7 2.《家畜繁殖学》本科教材，高等教育出版社（教育部远程教材），2004.5 3．《动物科学专业英语》本科教材，哈尔滨工程出版社，2007.1 4.《哺乳动物配子与胚胎工程》本科教材，东北农业大学出版，2005.1 5．《家畜繁殖学实验实习指导》本科教材，东北农业大学出版，2014.4 三、在研课题 1.2017.7-2020.12，牛定时输精与妊娠诊断技术研发，国家重点研发专项（畜禽繁殖调控技术研发）子项，主持 2.2017.10-2020.12，FSH通过CDC25B对犊牛睾丸支持细胞增殖调控的研究，黑龙江省自然科学基金，主持 |
学校主页