个人简历

1． 教育状况

2010.09-2014.06：东北农业大学新葡亰8883ent，动物科学，学士

2014.09-2017.06：东北农业大学新葡亰8883ent，动物营养与饲料科学，硕士

2017.09-2021.06：东北农业大学新葡亰8883ent，动物营养与饲料科学，博士

2．工作经历

2021.10-至今：东北农业大学新葡亰8883ent，副教授，硕导

著作论文

代表性论文（第一作者）

1. Changxuan Shao#, Yongjie Zhu#, Qiao Jian, Zhenheng Lai, Peng Tan, Guoyu Li, Anshan Shan*. Cross-Strand Interaction, Central Bending, and Sequence Pattern Act as Biomodulators of Simplified β-Hairpin Antimicrobial Amphiphiles. Small, 2021, 17(7), 2003899. (中科院1区top，IF=13.281)

2. Chensi Wang#, Changxuan Shao#, Yuxin Fang, Jiajun Wang, Na Dong*, Anshan Shan*. Binding loop of sunflower trypsin inhibitor 1 serves as a design motif for proteolysis- resistant antimicrobial peptides. Acta Biomaterialia, 2021,124:254-269. (中科院1区top，IF=8.947)

3. Yongjie Zhu#, Changxuan Shao#, Guoyu Li., Zhenheng Lai., Peng Tan., Qiao Jian., Baojing Cheng., Anshan Shan. Rational Avoidance of Protease Cleavage Sites and Symmetrical End-Tagging Significantly Enhances the Stability and Therapeutic Potential of Antimicrobial Peptides. Journal of Medicinal Chemistry, 2020, 63(17), 9421-9435. (中科院2区top，IF=7.446)

4. Lin Xu#; Changxuan Shao#; Guoyu Li; Anshan Shan*; Shuli chou; Jiajun Wang; Qingquan Ma; Na Dong; conversion of broad-spectrum antimicrobial peptides into species-specific antimicrobials capable of precisely targeting pathogenic bacteria. Scientific Reports, 2020, 10: 944. (中科院3区，IF=4.379)

5. Changxuan Shao#, Weizhong Li#, Peng Tan, Anshan Shan*, Xiujing Dou, Deying Ma*, Chunyu Liu. Symmetrical modification of minimized dermaseptins to extend the spectrum of antimicrobials with endotoxin neutralization potency. International Journal of Molecular Sciences, 2019, 20 (6): 1417. (中科院2区top，IF=5.923)

6. Changxuan Shao#; Yongjie Zhu#; Zhenheng Lai; Peng Tan; Anshan Shan*; Antimicrobial peptides with protease stability: progress and perspective. Future Medicinal Chemistry, 2019, 11: 2047-2050. (中科院2区，IF=3.808)

7. Changxuan Shao#; Weizhong Li#; Zhenheng Lai; Muhammad Usman Akhtar; Na Dong; Anshan Shan*; Deying Ma; Effect of terminal arrangement of tryptophan on biological activity of symmetric α-helix-forming peptides. Chemical Biology & Drug Design, 2019, 94: 2051-2063. (中科院3区，IF=2.817)

8. Changxuan Shao; Haotian Tian; Tianyu Wang; Zhihua Wang; Shuli Chou; Anshan Shan*; Baojing Cheng; Central β-turn increases the cell selectivity of imperfectly amphipathic α-helical peptides, Acta Biomaterialia, 2018, 69: 243-255. (中科院1区top，IF=8.947)

在研课题

1．东北农业大学高层次人才引进项目-饲用型抗微生物肽的创制、工艺创新与应用价值评定，2021.10-2024.10，主持。

教学工作

暂无

科技奖励与其他

东农学者计划“学术骨干”；

国家首批教育部全国高校“百个研究生样板党支部”；

第二批教育部全国高校“百名研究生党员标兵”；

中国科学院青年创新促进会第七届研究生学术论坛一等奖；

2014届、2017届、2020届东农校友年级理事。